AV Magnivisualizer– Indigenous Device to Detect Cervical Cancer

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Cervical cancer occurs when abnormal cells on the cervix grow out of control. The cervix is the lower part of the uterus that opens into the vagina. Cervical cancer can often be successfully treated when it's found early. It is usually found at a very early stage through a Pap test.
Most cervical cancer is caused by a virus called human papillomavirus, or HPV. Someone can get HPV by having sexual contact with someone who has it. There are many types of the HPV virus. Not all types of HPV cause cervical cancer. Some of them cause genital warts, but other types may not cause any symptoms.
Cervical cancer is the leading malignancy among women in the developing world.
80% of all cases occur in the countries of sub-Saharan Africa, South Asia and Latin America.
In developing countries like India, the incidence may be up to six times higher than in developed countries due to lack of cyto- screening programs, other alternative strategies such as visual inspection with acetic acid (VIA) were tried to detect early cancerous lesions of cervix in low resource setting.
Problem with visual test is the extreme variation in sensitivity and low specificity.
What is AV Magnivisualizer ?
AV Magnivisualizer was designed and developed by DR.Aditya Parashari to improve the sensitivity of VIA and reduce the non specific results as much as possible.
It is the indigenous device to detect the cervical cancer.
This instrument was also found suitable to examine the oral cavity for the presence of any pre-cancer and cancer lesions, where it improved the detection rate of lesions more than 1.5 times (50%) compared to tungsten light of torch in the field.
It is low cost illumination and magnifying device for visualizing the cervix, which can be used, where there is no cytology and colposcopy facilities are not available. This device can also be used where even there is no electricity because it can be operated on 12 volt portable rechargeable battery.
Features of AV Magnivisualizer: i) has color temperature of 5500K – 6000K with full visible spectrum of light (wave length 4000ºA to 7800ºA). Human eyes are most sensitive for 5550ºA in yellow-green spectrum of visible light. Ii) Proper heat shield and special filter are provided to check the heat emitted by bulb. iii) Interchangeable magnifying lenses (1+,2+,4+ diopter) are provided for different magnification. Recommended 1+ and 4+ diopter combination to be used.
1. The utility survey for both cervical and oral cavity examination clearly revealed that 95 to 100% of the examiners were comfortable with the instrument and were satisfied with different parameters of the examination.
2. The comparative performance of Magnivisualizer vs tungsten light for the examination of the cervix (20.5% vs. 12.7%) and oral cavity (24.8% vs. 16.5%) revealed that Magnivisualizer detected 1.5 to 1.6 times more lesions compared to tungsten light.
3. Ninety percent of the cervical lesions detected by Magnivisualizer were also detected positive by cytology (LSIL +).
4. Ninety three percent of oral lesions detected by Magnivisualizer were also detected by cytology (Benign, dysplastic, or cancerous lesions).
5. Magnivisualizer could differentiate oral lesions most efficiently (95%) vs. Tungsten light (44.3%).
The instrument worked well in different categories of personnel’s with different educational and training backgrounds. The performance was highly satisfactory in both clinic and field settings. Magnivisualizer has been found to be a good option for examination of cervix and oral cavity for early detection of pre-cancers and cancerous lesions.
Shortcomings in infrastructure and a lack of trained personals, screening by visual inspection with the AV Magnivisualizer offers an alternative means to detect most early cancerous and high grade lesions that have a high potential for progression.
It is cheap as it is available for Rs. 10,000 compared with the same other kind of products which costs lakhs to purchase it.
The simple technique of visual inspection by means of the AV Magnivisualizer can be undertaken even in a primary health care center; the only additional requirement is an examination table.
A biopsy can be performed at the same time, whereas with the result of the cytological investigation is not known for some time afterwards. See and treat approach can easily adopted.
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